The health benefits of shiitake mushrooms have been recognized for over 6000 years. In addition to being an excellent source of vitamins B-complex and D, shiitakes provide immune support by stimulating the macrophages which inhibit cancer cells. They also provide a protective effect against inflammation, toxins, and radiation. Shiitakes have been studied for their ability to block tumor growth and promote cell death in damaged cells. For best benefit, sauté lightly for about 7 minutes, add to miso soup or salads, and many other dishes.